Emulsifiers are widely used in the food industry and are approved for consumption by the FSA. But emerging research suggests some may not be as harmless as once thought – particularly when it comes to gut health and inflammation.
In 2017, the European Food Safety Authority identified food emulsifiers as an emerging risk in light of the research which was beginning to surface.
1. Potential gut health impact
Some studies are starting to link emulsifiers in food to the alteration of gut microbiota. This is the balance of beneficial bacteria in the digestive system, which has been found to govern many bodily functions from your metabolism to your mood.
One study in mice found that certain emulsifiers – specifically carboxymethylcellulose and polysorbate-80 – decreased the diversity of their gut bacteria and disrupted the mucus gut barrier. This increased gut permeability (often referred to as "leaky gut”). (1) It meant that bacteria and other molecules were more likely to leak through the gut lining, causing inflammation.
This study was conducted in mice, not humans, so it doesn’t confirm that the same process occurs when we consume emulsifiers. Nevertheless, further studies have begun to show similarly negative effects in humans, as we’ll find out.
2. Inflammation concerns
A study of the same two emulsifiers on human gut microbiota found that “commonly used emulsifiers can directly alter gut microbiota in a manner expected to promote intestinal inflammation.” (2)
Chronic inflammation is associated with various inflammatory bowel diseases, such as Crohn’s disease, ulcerative colitis, and other metabolic disorders. (3,4)
One small human study asked patients in remission with ulcerative colitis to test the removal of carrageenan from their diet for up to 12 months. Some patients were given a carrageenan capsule daily, while others were given a placebo. Three of the five patients taking the carrageenan capsule relapsed, while none of those taking a placebo capsule did. (5)